Bridging Laboratory and Field Research for Genetic Control by B.G.J. Knols, C. Louis

By B.G.J. Knols, C. Louis

Modern study on genetic keep watch over of disease-transmitting bugs understands sorts of scientists: those who paintings within the laboratory and people referred to as ‘field people’. during the last decade, either teams appear to have built differing learn priorities, handle essentially various facets in the total self-discipline of infectious-disease regulate, and worse, have constructed a systematic ‘language’ that's not understood through the ‘other’ social gathering. This hole widens on a daily basis, among the North and the South, among ecologists and molecular biologists, geneticists and behaviourists, and so forth. the necessity to enhance a standard study time table that bridges this hole has been pointed out as a best precedence via all events concerned. in simple terms then shall the target of constructing acceptable genetic-control innovations for vectors of ailment turn into fact. This ebook is the mirrored image of a workshop, held in Nairobi (Kenya) in July 2004. It introduced jointly an exceptional illustration of either molecular and ecological study and, for the 1st time, incorporated an important variety of researchers from disease-endemic nations.

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Extra info for Bridging Laboratory and Field Research for Genetic Control of Disease Vectors (Wageningen UR Frontis Series)

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Or urban An. stephensi populations surrounded by An. culicifacies. Others have suggested going beyond ‘ecological islands’ described above, and move to physical islands. Genetic-control trials have delivered dramatic successes through eradication of target pests, such as the eradication of Glossina austeni from the island of Zanzibar by 1997. With regard to the application of GM approaches for disease-vector control, further containment (in terms of selecting isolated populations) is needed, to overcome potential adverse effects of the introduction of GM insects.

E. knowledge of the local vector population, and partial to full isolation of the target population. CI trials in Myanmar were conducted in a village surrounded by rice fields, where the target pest did not occur. In Kenya, genetic-control trials against Ae. aegypti in the 1970s focused on villages and a small area surrounding them. The necessity for applying genetic control against isolated populations remains valid today. It has been proposed to target Anopheles arabiensis populations in urban areas surrounded by An.

Hominivorax from Libya (Wyss 2000; Lindquist 1993). A programme of aerial releases which moved steadily forward was able to deal with the problem of immigration by ensuring that females were engaged in sterile matings before beginning their migratory flights, achieving eradication of this major veterinary pest, which can also cause myiasis in humans, at a cost that was rapidly repaid by elimination of the cattle losses caused by the Screwworm. At one point it was claimed that behavioural barriers existed between different sub-populations of Screwworms (Richardson, Ellison and Averhoff 1982), but this was never supported by many data (Krafsur 1998) and the successful eradication all the way to Panama with flies reared from a single captive population indicates that this kind of biological complexity was not a real problem.

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